Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat Loci in Mycobacterium ulcerans.

نویسندگان

  • Anthony Ablordey
  • Markus Hilty
  • Pieter Stragier
  • Jean Swings
  • Françoise Portaels
چکیده

We analyzed a set of variable-number tandem-repeat (VNTR) loci to assess their nucleotide sequence diversity in isolates of three Mycobacterium ulcerans genotypes. Sequence variants in two loci resulted in intraspecies resolution of Southeast Asian and Asian genotypes in contrast to a homogenous sequence composition among African isolates. Nucleotide sequence polymorphism in repeat units can enhance discrimination of VNTR loci.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 43 10  شماره 

صفحات  -

تاریخ انتشار 2005